Join discussion leaders Shan Siddiqi, MD (BWH) and Nolan Williams, MD (Stanford) as they engage leading experts from around the world on important topics facing the rapidly emerging field of brain stimulation. Through a series of presentations and discussions, this summit will establish a network of key opinion leaders to yield consensus on specific debates and build an intellectual framework to allow this transformative subspecialty to launch and grow.
Brigham & Women’s Hospital, Boston, MA
Louis Bornstein Family Amphitheater
Brigham and Women’s Hospital
45 Francis Street
Shan Siddiqi, MD, Brigham & Women’s Hospital, Harvard Medical School
Nolan Williams, MD, Stanford University School of Medicine
We aim for this summit to:
- Establish an intellectual framework along which this subspecialty can launch and grow.
- Create a network of experts that can guide the subspecialty forward as it evolves.
- Yield a consensus statement on specific debates in this field (see below)
STATE OF SCIENCE at Bornstein Amphitheater. 10-minute lectures from attendees. Open to all.
|12:00 – 1:00
Stimulating Brain Circuits from Different Vantage Points
Recent data suggest that TMS, DBS, and lesions can treat the same symptom by modulating different parts of the same brain circuit. However, different tools are used by different specialists with minimal cross-talk. There may be ways for these tools to complement each other; for instance, TMS may be used to noninvasively probe a circuit to identify the right DBS/FUS targets and the right candidate patients before surgery.
In this session, speakers will present ideas for using these techniques to complement one another.
|1:00 – 2:00
Complementary, Competing, and Converging Tools
There are different approaches to identifying treatment targets and parameters beyond those that are currently in use. Some of these approaches are complementary and others are competing, but in many cases these different approaches may converge on a common answer.
Michael Sugrue – neurosurgeon
Mark Eldaief – neurologist/cognitive
Desmond Oathes – clinical psychologist
Damiaan Denys – psychiatrist/interventional
Noreen Bukhari – neurologist/movement
|2:00 – 2:30
|2:30 – 3:30
Exploring the Parameter Space and Monitoring Outcomes
There are very few brain stimulation protocols that are currently in clinical practice, and they are often oversimplified as “excitatory” versus “inhibitory.” Several components can be further optimized, such as treatment parameters (e.g. frequency, intensity), state dependence, and synergistic pharmacotherapy. There are emerging data for how each of these components may be optimized and their outcomes may be monitored.
Alik Widge -psychiatrist/interventional
Joshua Brown – psychiatrist/neurologist
Andrew Leuchter – psychiatrist/TMS
Moushin Shafi – neurologist/epilepsy
Conor Liston – psychiatrist/basic science
Alex McGirr – psychiatrist/TMS
|3:30 – 4:30
Clinical Standards and Off-label Treatment
Many clinicians are using unorthodox brain stimulation protocols. Some of these protocols are designed to maximize revenue rather than maximizing risk-benefit to the patient. On the other hand, off-label protocols may be appropriate when there is early-stage evidence that the benefits outweigh the risks and the patient has not responded to conventional treatment. There are no clear guidelines for what constitutes an acceptable amount of evidence for applying off-label treatment.
Brian Kopell – neurosurgeon
Leo Chen – psychiatrist/TMS
Mohammed Ahmed – neuropsychiatrist
David Carreon – psychiatrist/TMS
Rebecca Allen – neuropsychiatrist
Jonathan Downar – psychiatrist/TMS
|4:30 – 5:00
|5:00 – 6:00
Additional topics that do not fall into the above categories, but have a high probability of translating to brain stimulation clinical practice in the near future.
Volker Coenen – neurosurgeon
Scott Aaronson – psychiatrist/interventional
Catherine Chu – neurologist/child
Colleen Hanlon – clinical neuroscientist
Noah Philip – psychiatrist/interventional
Nicole Peterson – clinical neuroscientist
Louis Bornstein Family Amphitheater
Enter 15 Francis Street (Peter Bent Brigham Building)
Take a left and walk down the Pike (2nd floor)
Bornstein is between Elevator H and G on the Pike, right side.
From 75 Francis St – Main Lobby
Take the escalator up to the second floor and turn right.
Walk past the gift shop and through the Tower elevator bank to enter the Pike
Bornstein is after Elevator H, on the left.
From 45 Francis Street
Enter through the 45 Francis street entrance, head straight towards The Pike, take a left and Bornstein Family Amphitheater will be on your right between Elevator H and G.