Marc Sabatine

Marc Sabatine, MD, MPH

Professor, Medicine
Lewis Dexter, MD, Distinguished Chair in Cardiovascular Medicine, BWH
Chairman of the Thrombolysis in Myocardial Infarcation (TIMI) Study Group

Brigham Research Institute Director (2018-2020)
Professor in Medicine, Harvard Medical School
Lewis Dexter, MD, Distinguished Chair in Cardiovascular Medicine, Brigham and Women’s Hospital
Chairman of the Thrombolysis in Myocardial Infarction (TIMI) Group


Highlights from the BRI Director 2018-2020

During Fiscal Year 2019, the Brigham Research Institute provided support to activities defined through a BRI-wide strategic assessment and planning process the previous year. Research Roundtables, thematic discussions focused on areas aligned with programs/centers to define priorities in those areas and foster innovation and collaboration.

The BRI distributed $3.22 Million in internal awards in FY2019. These awards ranged from $500 poster awards to the $500,000 BRI Director’s Transformative Award. The BRI implemented the solicitation and selection process for the newly launched President’s Scholar Awards, intended to support and recognize Assistant or Associate Professors at the Brigham who have made outstanding contributions to their chosen field of research and who have demonstrated exceptional potential.

We continued hosting bi-annual research faculty and trainee lunches and in 2019, hosting two lunches for each group:

  • Postdocs and Trainees
  • Instructors
  • Assistant Professors
  • Associate Professors
  • Professors

Our Scientific Advisory Board added a new member, now comprised of nine highly accomplished scientific and industry leaders who provide guidance to enrich our strategies to promote biomedical advances at the Brigham. The Board meets annually.

The BRI launched a new monthly newsletter, Science Spotlight, to celebrate Brigham faculty publications in high impact journals and keep the research community informed about the work of their peers.

Brigham researchers published more than 9,400 publications in 2019 (ranking second among healthcare institutions in the world in terms of total article count, according to Nature Index), with close to 500 of these in top-rated journals.

Brigham research revenue was $698 Million in FY2019, representing nearly a quarter of the hospital’s revenue.

Marc S. Sabatine, MD, MPH is Chairman of the Thrombolysis in Myocardial Infarction (TIMI) Study Group, the Lewis Dexter, MD, Distinguished Chair in Cardiovascular Medicine at Brigham and Women’s Hospital (BWH), and a Professor of Medicine at Harvard Medical School (HMS).

Dr. Sabatine graduated magna cum laude from Harvard College and received his medical degree magna cum laude from HMS. He did his Internal Medicine residency, Chief Residency, and Cardiology clinical fellowship at the Massachusetts General Hospital (MGH). He received a Master of Public Health degree from the Harvard School of Public Health. Dr. Sabatine is board certified in Internal Medicine and Cardiology and attends in the coronary care units at both BWH & MGH. He is a Fellow of the American Heart Association, the American College of Cardiology, and the European Society of Cardiology.

As Chairman of the TIMI Study Group, Dr. Sabatine leads an Academic Research Organization that includes a dozen staff cardiologists and whose mission over the past 30 years has been to advance the knowledge and care of patients suffering from cardiovascular disease and its risk factors. To that end, Dr. Sabatine has led several large-scale, international, randomized controlled trials of novel antithrombotic, lipid-lowering, and other pharmacotherapies. A pioneer in the multimarker approach to risk stratification, Dr. Sabatine has several NIH grants supporting the application of proteomics and metabolomics for discovery of novel biomarkers. He has a long-standing interest in pharmacogenetics and has made seminal observations on the ability to use genetics for personalized medicine.

Dr. Sabatine has authored over 200 original research, peer-reviewed articles including in the New England Journal of MedicineJAMA, and the Lancet. Dr. Sabatine has given Cardiology or Medical Grand Rounds at top academic centers around the world and has authored numerous review articles and book chapters. He is the recipient of multiple honors and awards including the ACC Zipes Distinguished Young Scientist Award and has been inducted into the American Society of Clinical Investigation. He is on the writing committees for several ACC/AHA practice guidelines. He is a Deputy Editor for JAMA Cardiology.