Our scientists have led lung cancer detection, staging and treatment including new intraoperative imaging approaches to localize and guide surgical removal of lung cancers, reduce morbidity before and after surgery, and studies of new targeted cancer treatments.

We have contributed to the development of more than 30 study populations for respiratory research with >100,000 subjects subjects for genetic studies ranging from genome-wide association analysis to large-scale DNA sequencing sequencing and transcriptomics, metabolomics, epigenetics, etc. These Precision Medicine efforts are already translating research advances to improved clinical care, such as the development of the BWH Pulmonary Genetics Clinic.

Notably, our research has recently yielded the first-of-its-kind in vitro model of the human lower lung which is enabling active research into how COVID-19 particles travel through our airways and how various therapies such as remdesivir impact virus replication.